5-Methoxyindole-3-acetic acid ( 5-Methoxyindoleacetic acid; Methoxyindoleacetic acid )

Catalog No. M26543 CAS No. 3471-31-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

5-Methoxyindole-3-acetic acid
Note

Research use only, not for human use.
Brief Description

5-Methoxyindole-3-acetic acid is a metabolite of Melatonin and is isolated from pineal tissue.
Description

5-Methoxyindole-3-acetic acid is a metabolite of Melatonin and is isolated from pineal tissue.(In Vivo):Transplacental administration of 5-methoxyindole-3-acetic acid possessing blastomogenic activity induced the development of malignant and benign neoplasms (lymphosarcomas, adenomas, hepatomas and other tumours) in 84% of C57BL/6 mouse progeny. The number of neoplasms was significantly higher, than in the control, they appeared earlier and were more malignant.
Synonyms

5-Methoxyindoleacetic acid; Methoxyindoleacetic acid
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Akt2; Apoptosis; Autophagy; p70S6K; PKA
Research Area

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Indication

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1. Wang FZ, et al. CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition. Biochimie. 2014;103:118-125.

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