5-Methoxyindole-3-acetic acid

CAS No. 3471-31-6

5-Methoxyindole-3-acetic acid ( 5-Methoxyindoleacetic acid; Methoxyindoleacetic acid )

Catalog No. M26543 CAS No. 3471-31-6

5-Methoxyindole-3-acetic acid is a metabolite of Melatonin and is isolated from pineal tissue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-Methoxyindole-3-acetic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Methoxyindole-3-acetic acid is a metabolite of Melatonin and is isolated from pineal tissue.
  • Description
    5-Methoxyindole-3-acetic acid is a metabolite of Melatonin and is isolated from pineal tissue.(In Vivo):Transplacental administration of 5-methoxyindole-3-acetic acid possessing blastomogenic activity induced the development of malignant and benign neoplasms (lymphosarcomas, adenomas, hepatomas and other tumours) in 84% of C57BL/6 mouse progeny. The number of neoplasms was significantly higher, than in the control, they appeared earlier and were more malignant.
  • Synonyms
    5-Methoxyindoleacetic acid; Methoxyindoleacetic acid
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Akt2; Apoptosis; Autophagy; p70S6K; PKA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3471-31-6
  • Formula Weight
    205.2
  • Molecular Formula
    C11H11NO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccc2[nH]cc(CC(O)=O)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang FZ, et al. CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition. Biochimie. 2014;103:118-125.
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